This part of your brain processes the most complex executive functions. Consequently, damage to the prefrontal area causes memory problems, attention problems, issues with language and perception, among other things. They can begin in the frontal lobe, the temporal lobe, or both. Individually, the paired lobes are known as the left and right frontal cortex. The frontal lobe is the largest lobe accounting for 41% of the total neocortical volume 8..

Dysexecutive syndrome (DES) stems from damage to the frontal lobe, more specifically in the prefrontal region.

Frontal lobe disorder is an impairment of the frontal lobe that occurs due to disease or head trauma. The frontal lobes, situated above the eyes and behind the forehead on the right and left sides of the brain, direct executive functioning. Recently, more attention has been paid to the biological basis of amotivational syndrome.
The frontal lobe is part of the brain’s cerebral cortex.

Several studies using MRI, SPECT or neuropsychological measures have revealed white matter changes, hypoperfusion in the frontal cortex of the brain and impairment of frontal lobe function. The frontal lobe of the brain plays a key role in higher mental functions such as motivation, planning, social behaviour, and speech production. The frontal lobe is the largest lobe of the brain lying in front of the central sulcus. Initially, frontotemporal disorders leave other brain regions untouched, including those that control short-term memory. It is divided into 3 major areas defined by their anatomy and function. The frontal lobe resides largely in the anterior cranial fossa, lying on the orbital plate of the frontal bone.Its most anterior part is known as the frontal pole, and extends posteriorly to the central (Rolandic) sulcus which separates it from the parietal lobe. Gross anatomy. Hama S, Yamashita H, Shigenobu M, Watanabe A, Kurisu K, Yamawaki S. Post-stroke affective or apathetic depression and lesion location: left frontal lobe and bilateral basal ganglia.



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