It affects over 2,000 people a year in the U.S. and usually occurs from April until September. Presumptive treatment with doxycycline is recommended in patients … Doxycycline is the recommended antibiotic treatment for RMSF in adults and children of all ages. An early course of the antibiotic doxycycline is the best treatment. Rocky Mountain Spotted Fever is a deadly disease caused by a tick bite from an infected tick. Doxycycline is the treatment of choice for RMSF, and all other tickborne rickettsial diseases. Early treatment with the antibiotic doxycycline can prevent death and severe illness. Rocky Mountain spotted fever (RMSF) is a bacterial disease spread through the bite of an infected tick. Page last reviewed: October 26, 2018 Use of antibiotics other than doxycycline is associated with a higher risk of fatal outcome from RMSF. Many people die within eight days of a tick bite unless they get medical help. Rocky Mountain spotted fever (RMSF) is an infection caused by the bite of an infected tick. “It’s a microbe where, if you develop symptoms, you need antibiotics to try to knock down the infection as quickly as possible .” RMSF can be life-threatening. But, it can occur anytime during the year where the weather is warm. “There are a lot of variables that play into why a person becomes sick with Rocky Mountain spotted fever, but if they become ill, they become very ill,” says Dr. Rawls. Most people who get sick with RMSF will have a fever, headache, and rash. RMSF can be deadly if not treated early with the right antibiotic.



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