Hydatidiform mole is a benign gestational trophoblastic disease which is a mass of swollen, cystically dilated, chorionic villi, which appear grossly as grapelike structures. [Google Scholar] 76: McConnell TG, Norris-Kirby A, Hagenkord JM, Ronnett BM, Murphy KM. This is a recurrent autosomal recessive disorder. ... Familial hydatidiform mole (biparental complete mole) A rare clinical form of complete hydatidiform mole is familial recurrent hydatidiform mole, where the moles are diploid but biparental. 2004; 17 (9): 1155 – 1160. Hydatidiform mole, in human pregnancy, abnormal growth of the chorion, the outermost vascular membrane that in a normal pregnancy would enclose the embryo and ultimately give rise to the placenta.In the situation in which the hydatidiform mole develops, the embryo is usually either absent or dead. Estimated rate of hydatidiform moles is 7.5 per 10,000 pregnancies (Am J Obstet Gynecol 1986;154:906) More frequent than complete mole; in a study of pathological examination of first and second trimester abortions, the incidence of partial mole was 1:695 compared to complete mole, 1:1,945 (Int J Gynecol Pathol 1993;12:315) Risk of partial mole was 11 cases per 10,000 live births … It is a type of gestational trophoblastic disease. Mod Pathol. There are two types of Hydatidiform mole 1. Hydatidiform mole. Partial Hydatidiform Mole Focused Partial Hydatidiform Mole with stained slides of pathology. Complete hydatidiform mole retaining a chromosome 11 of maternal origin: molecular genetic analysis of a case. Department of Pathology & Laboratory Medicine, Rutgers‐New Jersey Medical School, Newark, NJ, USA.
Molar pregnancy is a form of gestational trophoblastic disease that results from a defective fertilization process where the zygote inherits two copies of paternal DNA instead of one. Visual survey of surgical pathology with 10445 high-quality images of benign and malignant neoplasms & related entities. Partial hydatidiform mole Complete hydatidiform mole 2. Hydatidiform mole genotyping is used to evaluate for molar pregnancy (hydatidiform mole) in products of conception with abnormal villous morphology.
Complete hydatidiform mole with retained maternal chromosomes 6 and 11.
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