The same innovation occurred in other studies that used geotechnology as an important tool to demonstrate findings. Leprosy is a chronic infection caused by the acid-fast, rod-shaped bacillus Mycobacterium leprae.

Depending on the form of leprosy suspected by the treating physician, the following specimens may be collected: Skin smears from the earlobes, elbows, and knees; Skin biopsy from edges of active patches; Nerve biopsy from thickened nerves; Skin and nerve biopsy. Leprosy, also known as Hansen's disease (HD), is a long-term infection by the bacteria Mycobacterium leprae or Mycobacterium lepromatosis. Sakamuri et al. A gene is purified and then put into the mice, then they are exposed to M.leprae. In an unvaccinated animal, there is a small growth in the footpad that indicates infection.

The identification of the formation of urban clusters of leprosy determined by territorial space and characterized by clinical form together with the time at onset of the disease seems to be innovative in research. The route of transmission of leprosy remained a matter of debate. His discovery demonstrated that leprosy is an infectious disease propagated by a specific microorganism. Biopsies are needed to definitively confirm a diagnosis of Hansen’s disease and to classify the disease, and slit skin smear … Leprosy infection is measured in mice by observation of the footpad.

The diagnosis of leprosy is based on clinical examination, bacilloscopy and histopathology. Hansen was able to identify the organism under the microscope because its propensity to collect iron caused it to appear brownish in colour compared with the tissue itself.

Infection can lead to damage of the nerves, respiratory tract, skin, and eyes. Leprosy is a chronic, progressive bacterial infection caused by the bacterium Mycobacterium leprae. leprae antibodies, while people with LL leprosy skew toward a Th2 pole and a strong antibody-mediated responses that do not control bacilli replication and are usually seropositive [8;9].



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